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Book chapterFletcher A, Pearson J, Molleson T, et al., 2014,
Beneath the surface: imaging techniques and the Jericho Skull
, Regarding the Dead Human Remains in the British Museum, Publisher: British Museum Publications Limited, ISBN: 9780861591978A key publication on the British Museum's approach to the ethical issues surrounding the inclusion of human remains in museum collections and possible solutions to the dilemmas relating to their curation, storage, access management and ...
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Conference paperLangley RE, Trinh D, Jovic G, et al., 2014, , 50th Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Publisher: LIPPINCOTT WILLIAMS & WILKINS, ISSN: 0732-183X
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- Citations: 1
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Journal articleAtallah L, Wiik A, Lo B, et al., 2014, , PHYSIOLOGICAL MEASUREMENT, Vol: 35, Pages: N29-N40, ISSN: 0967-3334
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- Citations: 18
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Conference paperCoudrillier B, Abel RL, Albon J, et al., 2014,
Micro-computed Tomography (μCT) for the Structural Analysis of the Lamina Cribrosa (LC)
, Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404- Cite
- Citations: 1
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Journal articleDuffell LD, Southgate DFL, Gulati V, et al., 2014, , GAIT & POSTURE, Vol: 39, Pages: 1057-1061, ISSN: 0966-6362
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- Citations: 74
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Conference paperEthier CR, Campbell IC, Coudrillier B, et al., 2014,
Automated detection of Lamina Cribrosa (LC) beam microarchitecture from imaging data using a Frangi filter
, Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404 -
Conference paperCampbell IC, Coudrillier B, Abel RL, et al., 2014,
Effects of Lamina Cribrosa Microarchitecture on Biomechanics in Glaucoma
, Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, ISSN: 0146-0404 -
Journal articleGupte CM, Schaerf DA, Sandison A, et al., 2014, , ISRN Anatomy, Vol: 2014, ISSN: 2314-4726
Aim. To investigate the existence of neural structures within the meniscofemoral ligaments (MFLs) of the human knee. Methods. The MFLs from 8 human cadaveric knees were harvested. 5 μm sections were H&E-stained and examined under light microscopy. The harvested ligaments were then stained using an S100 monoclonal antibody utilising the ABC technique to detect neural components. Further examination was performed on 60–80 nm sections under electron microscopy. Results. Of the 8 knees, 6 were suitable for examination. From these both MFLs existed in 3, only anterior MFLs were present in 2, and an isolated posterior MFL existed in 1. Out of the 9 MFLs, 4 demonstrated neural structures on light and electron microscopy and this was confirmed with S100 staining. The ultrastructure of these neural components was morphologically similar to mechanoreceptors. Conclusion. Neural structures are present in MFLs near to their meniscal attachments. It is likely that the meniscofemoral ligaments contribute not only as passive secondary restraints to posterior draw but more importantly to proprioception and may therefore play an active role in providing a neurosensory feedback loop. This may be particularly important when the primary restraint has reduced function as in the posterior cruciate ligament—deficient human knee.
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Journal articleNewman SD, Lotfibakhshaiesh N, O'Donnell M, et al., 2014, , TISSUE ENGINEERING PART A, Vol: 20, Pages: 1850-1857, ISSN: 1937-3341
The use of endosseous implants is firmly established in skeletal reconstructive surgery, with rapid and permanent fixation of prostheses being a highly desirable feature. Implant coatings composed of hydroxyapatite (HA) have become the standard and have been used with some success in prolonging the time to revision surgery, but aseptic loosening remains a significant issue. The development of a new generation of more biologically active coatings is a promising approach for tackling this problem. Bioactive glasses are an ideal candidate material due to the osteostimulative properties of their dissolution products. However, to date, they have not been formulated with stability to devitrification or thermal expansion coefficients (TECs) that are suitable for stable coating onto metal implants while still retaining their bioactive properties. Here, we present a strontium-substituted bioactive glass (SrBG) implant coating which has been designed to encourage peri-implant bone formation and with a TEC similar to that of HA. The coating can be successfully applied to roughened Ti6Al4V and after implantation into the distal femur and proximal tibia of twenty-seven New Zealand White rabbits for 6, 12, or 24 weeks, it produced no adverse tissue reaction. The glass dissolved over a 6 week period, stimulating enhanced peri-implant bone formation compared with matched HA coated implants in the contralateral limb. Furthermore, superior mechanical fixation was evident in the SrBG group after 24 weeks of implantation. We propose that this coating has the potential to enhance implant fixation in a variety of orthopedic reconstructive surgery applications.
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Journal articleCobb JP, 2014, , BMJ-BRITISH MEDICAL JOURNAL, Vol: 348, ISSN: 1756-1833
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- Citations: 1
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Journal articleDodds AL, Halewood C, Gupte CM, et al., 2014, , BONE & JOINT JOURNAL, Vol: 96B, Pages: 325-331, ISSN: 2049-4394
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- Citations: 321
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Journal articleDuffell LD, Hope N, McGregor AH, 2014, , PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, Vol: 228, Pages: 206-210, ISSN: 0954-4119
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- Citations: 73
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Journal articleMcGregor AH, Probyn K, Cro S, et al., 2014, , J Evid Based Med, Vol: 7, Pages: 62-63
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Journal articleBuckeridge EM, Bull AMJ, Mcgregor AH, 2014, , SPORTS BIOMECHANICS, Vol: 13, Pages: 47-61, ISSN: 1476-3141
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- Citations: 25
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Conference paperSeah TET, Barrow A, Baskaradas A, et al., 2014,
A Virtual Reality System to Train Image Guided Placement of Kirschner-Wires for Distal Radius Fractures
, 6th International Symposium on Biomedical Simulation (ISBMS), Publisher: SPRINGER INT PUBLISHING AG, Pages: 20-29, ISSN: 0302-9743- Cite
- Citations: 6
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Conference paperSpulber I, Papi E, Chen Y-M, et al., 2014,
Development of a wireless multi-functional body sensing platform for smart garment integration
, IEEE Biomedical Circuits and Systems Conference (BioCAS), Publisher: IEEE, Pages: 157-160, ISSN: 2163-4025- Cite
- Citations: 3
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Journal articleHunt NC, Ghosh KM, Blain AP, et al., 2014, , J. Orthop. Res., Vol: 32, Pages: 1208-1213, ISSN: 1554-527X
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Journal articleVarma RK, Duffell LD, Nathwani D, et al., 2014, , BMJ OPEN, Vol: 4, ISSN: 2044-6055
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- Citations: 21
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Journal articleTay C, Khajuria A, Gupte C, 2014, , INTERNATIONAL JOURNAL OF SURGERY, Vol: 12, Pages: 626-633, ISSN: 1743-9191
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- Citations: 72
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Journal articleDavidson DJ, Shaukat YM, Jenabzadeh R, et al., 2013, , BMJ Case Rep, Vol: 2013
Spontaneous bilateral compartment syndrome is a very rare condition but one which requires swift diagnosis and urgent surgical decompression by fasciotomies in order to achieve the best outcome. We present the case of a 31-year-old HIV-positive man. The case highlights the perils of being sidetracked by an atypical clinical history instead of acting on the classical clinical examination findings. We will discuss the presentation and management of this patient, review the literature and highlight the key learning points. The most important learning point being that no matter how atypical the history, if a patient presents with limb pain out of proportion to the injury (with or without pain on passive stretch), sensory changes and a loss of motor power, then a diagnosis of acute compartment syndrome must be considered.
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